Canesten Thrush Duo

Do not use Canesten Thrush Duo Oral Capsule & External Cream without first consulting your doctor:

• If you are under 16 or over 60 years of age
• If you are allergic to any of the ingredients in Canesten Thrush Duo Oral Capsule & External Cream or other antifungals and other thrush treatments If you are taking any other medicine other than the Pill.
• If you are taking the antihistamine terfenadine or the prescription medicine cisapride
• If you have had thrush more than twice in the last six months
• If you have any disease or illness affecting your liver or kidneys or have had unexplained jaundice.
• If you suffer from any other chronic disease or illness.
• If you or your partner have had exposure to a sexually transmitted disease.
• If you are unsure of the cause of your symptoms.

Women only:

• If you are pregnant, suspect you might be pregnant or are breastfeeding.
• If you have any abnormal or irregular vaginal bleeding or a blood-stained discharge
• If you have vulval or vaginal sores, ulcers or blisters.
• If you are experiencing lower abdominal pain or burning sensation on passing water.
• If you are experiencing any adverse events such as redness, irritation or swelling associated with the treatment.
• If you are experiencing fever or chills, nausea, vomiting or diarrhoea.
• If you have foul-smelling vaginal discharge.

Men only:

• If your sexual partner does not have thrush.
• If you have penile sores, ulcers or blisters.
• If you have an abnormal penile discharge (leakage).
• If your penis has started to smell.
• If you have pain on passing urine.

Recurrent use (men and women): patients should be advised to consult their physician if the symptoms have not been relieved within one week of taking Canesten Oral Capsule. Canesten Oral Capsule can be used if the candidal infection returns after 7 days. However, if the candidal infection recurs more than twice within six months, patients should be advised to consult their GP.

See the enclosed medicine leaflet for product directions.

Capsule active ingredients: Fluconazole 150mg. Other ingredients: Lactose Monohydrate. Cream active ingredients: Clotrimazole 200mg (2% w/w). Other ingredients: Benzyl Alcohol, Polysorbate 60, Sorbitan Stearate, Cetyl Palmitate, Cetostearyl Alcohol, Octyldodecanol, Purified Water.

Like all medicines, Canesten Thrush Duo can cause side effects: Signs of an allergic reaction may include:

• Rash
• Swallowing or breathing problems
• Swelling of your lips, face, throat or tongue
• Weakness, feeling dizzy or faint
• Nausea

Capsule

If you experience any of the following, please contact your doctor or pharmacist immediately – you may need urgent medical attention:

• Severe condition with blistering and peeling of the skin, mouth, eyes or genitals
• Liver disorders with symptoms such as yellowing of the skin or eyes, dark urine or pale stools
• Seizures
• Change in heart rhythm or rate

Common side effects:

• headache
• stomach discomfort, diarrhoea, feeling sick, vomiting
• increases in blood tests of liver function
• rash

Uncommon side effects:

• reduction in red blood cells which can make skin pale and cause weakness or breathlessness
• decreased appetite
• inability to sleep, feeling drowsy
• fit, dizziness, the sensation of spinning, tingling, pricking or numbness, changes in sense of taste
• constipation, indigestion, wind, dry mouth
• muscle pain
• wheals, blistering (hives), itching, increased sweating
• fatigue, general feeling of being unwell, fever

Rare side effects:

• lower than normal white blood cells that help defend against infections and red blood cells that help to stop bleeding, respectively causing recurrent infections like cold and flu and increased bleeding/blood thinning (if you cut yourself)
• red or purple discolouration of the skin which may be caused by low platelet count, other blood cell changes
• blood chemistry changes (high blood levels of cholesterol, fats)
• low blood potassium
• shaking
• hair loss

Cream

After you apply the cream you might experience:

• Itching
• Rash
• Blisters
• Burning
• Discomfort
• Swelling
• Redness irritation or peeling of the skin